Midgestation metabolic constraint in purine metabolism drives distinct strategies for placenta and fetal growth
Weizhi Xu, Nancy De La Cruz, Andrea Woods, Dmitry Lokshtanov, Shihong Max Gao, Nawal A. Khan, Sylvia Wright, Maria E. Florian Rodriguez, Donald D. McIntire, Elaine L. Duryea, David B. Nelson, Catherine Y. Spong, Christina L. Herrera, Jacob H. Hanna, Sanjay R Srivatsan, , Ashley Solmonson
The paper shows that midgestational metabolic constraints in purine metabolism drive distinct strategies for placenta and fetal growth in mice and humans.
bioRxiv · Mar 18, 2026 · PreprintDevelopmental Biology