Factor VII activating protease (FSAP) inhibits the outcome of ischemic stroke in mouse models.
J.-Y. Kim, D. Manna, T. B. Leergaard, S. M. Kanse
This study shows that FSAP-SPD improves stroke outcomes in mice by enhancing clot lysis and reducing infarct volumes, while the inactive MI-isoform has no effect.
bioRxiv · Jan 12, 2022Biochemistry