Author

T. De

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Evolutionary Biology· 1

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Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1 Organism:yeast· 1

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D. Gresham· 1 shared F. Abdul-Rahman· 1 shared G. Avecilla· 1 shared I. Suresh· 1 shared J. Chuong· 1 shared J. Matthews· 1 shared N. Ben Nun· 1 shared N. Brandt· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperEvolutionary Biology

D. Gresham

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1 paper

Recent·Most cited

Template switching during DNA replication is a prevalent source of adaptive gene amplification

J. Chuong, N. Ben Nun, I. Suresh, J. Matthews, T. De, G. Avecilla, F. Abdul-Rahman, N. Brandt, Y. Ram, D. Gresham

The paper investigates how genomic architecture influences the formation and fitness of adaptive copy number variants (CNVs) in yeast, finding that template switching during DNA replication is a common mechanism for CNV generation.

bioRxiv · May 3, 2024Evolutionary Biology