CD26-negative and CD26-positive tissue-resident fibroblasts contribute to functionally distinct CAF subpopulations in breast cancer
J. M. Houthuijzen, R. de Bruijn, E. van der Burg, A. P. Drenth, E. Wientjens, T. Filipovic, E. Bullock, C. S. Brambillasca, M. Nieuwland, I. de Rink, F. van Diepen, S. Klarenbeek, R. Kerkhoven, V. Brunton, C. L. G. J. Scheele, , J. Jonkers
The paper identifies CD26-negative and CD26-positive tissue-resident fibroblasts as sources of distinct CAF subpopulations in breast cancer through single-cell transcriptomics and functional assays.
bioRxiv · Sep 27, 2022 · PreprintCancer Biology