Author

T. Issitt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:metabolomics· 1

Frequent Co-Authors

A. Mahomed· 2 shared G. J. Quinlan· 2 shared A. Burke-Gaffney· 1 shared A. Lawrie· 1 shared F. Almaghlouth· 1 shared G. W. Kagugube· 1 shared I. Panselinas· 1 shared J. S. Wort· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCell Biology

A. Mahomed

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The hepcidin-ferroportin axis influences mitochondrial function, proliferation, and migration in pulmonary artery endothelial and smooth muscle cells

T. Issitt, Q. Toe, S. L. Pedersen, T. Shackshaft, M. M. Ghazaly, L. West, N. D. Arnold, A. Mahomed, G. W. Kagugube, L. Ramakrishnan, A. Lawrie, J. S. Wort, G. J. Quinlan

bioRxiv · Oct 9, 2023 · PreprintCell Biology

Hypoxic volatile metabolic markers in the MDA-MB-231 breast cancer cell line

T. Issitt, M. Reilly, S. T. Sweeney, W. J. Brackenbury, K. Redeker

This study identifies four volatile organic compounds altered in MDA-MB-231 breast cancer cells under hypoxia using gas chromatography mass spectrometry.

bioRxiv · Mar 2, 2023 · PreprintCell Biology

Human pulmonary artery endothelial cells upregulate ACE2 expression in response to iron-regulatory elements: potential implications for SARS-CoV-2 infection of vascular endothelial cells.

Q. K. Toe, T. Issitt, A. Mahomed, I. Panselinas, F. Almaghlouth, A. Burke-Gaffney, S. J. Wort, G. J. Quinlan

This study shows that human pulmonary artery endothelial cells increase ACE2 expression in response to IL-6 and hepcidin, which are elevated in severe COVID-19 and high-risk populations.

bioRxiv · Apr 8, 2021 · PreprintCell Biology