Cell BiologybioRxivPreprint
Human pulmonary artery endothelial cells upregulate ACE2 expression in response to iron-regulatory elements: potential implications for SARS-CoV-2 infection of vascular endothelial cells.
Q. K. Toe, T. Issitt, A. Mahomed…·G. J. Quinlan
This study shows that human pulmonary artery endothelial cells increase ACE2 expression in response to IL-6 and hepcidin, which are elevated in severe COVID-19 and high-risk populations.
DOI 10.1101/2021.04.08.437687