PARP7 mono-ADP-ribosylates the Agonist Conformation of the Androgen Receptor in the Nucleus
T. Kamata, C.-S. Yang, B. M. Paschal
This study identifies PARP7's zinc finger domain as critical for its nuclear localization and ability to ADP-ribosylate the agonist conformation of the androgen receptor, influencing AR-dependent transcription.
bioRxiv · Jun 21, 2021Biochemistry