Targeting dermatophyte Cdc42 and Rac GTPase signaling to hinder hyphal elongation and virulence
M. Ishii, Y. Matsumoto, T. Yamada, H. Uga, T. Katada, S. Ohata
This study identifies Cdc42 and Rac GTPase inhibition as a strategy to block hyphal elongation and virulence in Trichophyton rubrum, with EHop-016 showing promise as an antifungal lead.
bioRxiv · Mar 4, 2024Microbiology