Blockade of stromal Gas6 alters cancer cell plasticity, activates NK cells and inhibits pancreatic cancer metastasis.
A. Mielgo, L. Ireland, T. Luckett, M. C. Schmid
This study shows that blocking Gas6 in pancreatic cancer reduces metastasis by reversing EMT and activating NK cells, suggesting Gas6 as a therapeutic target.
bioRxiv · Aug 12, 2019Cancer Biology