T. Marsoner

Multiple routes of adaptation to high levels of CIN and aneuploidy in budding yeast

This study shows yeast cells adapt to high chromosomal instability and aneuploidy by first acquiring beneficial aneuploidies, then developing suppressor mutations, and finally reducing aneuploidy levels.

The chromosomal passenger complex establishes chromosome biorientation via two parallel localization pathways

This study identifies two parallel pathways by which the CPC establishes chromosome biorientation in budding yeast through distinct localization mechanisms.