An easy-to-use microfluidic mechano-chemostat for tissues and organisms reveals that confined growth is accompanied with increased macromolecular crowding
Z. Ben Meriem, T. Mateo, J. Faccini, C. Denais, R. Dufour-Castan, C. Guynet, T. Merle, M. Suzanne, M. Di-Luoffo, J. Guillermet-Guibert, B. Alric, S. Landiech, L. Malaquin, F. Mesnilgrente, A. Laborde, , M. Delarue
This paper introduces a microfluidic device that enables controlled mechanical and chemical environments for studying biological samples, showing that confined growth increases macromolecular crowding.
bioRxiv · Mar 29, 2023 · PreprintBiophysics