The cryo-EM structure of ASK1 reveals an asymmetric architecture allosterically modulated by TRX1
K. Honzejkova, D. Kosek, V. Obsilova, T. Obsil
This study determines the cryo-EM structure of ASK1 and its complex with TRX1, revealing an asymmetric dimeric architecture and allosteric regulation mechanism.
bioRxiv · Dec 20, 2023Biochemistry