Author

T. Pammi

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Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

B. T. K. Nguyen· 1 shared E. Smith· 1 shared J. W. Modell· 1 shared L. W. Graeff· 1 shared M. J. Stoltzfus· 1 shared R. E. Workman· 1 shared S. M. Sebald· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

B. T. K. Nguyen

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1 paper

Recent·Most cited

MicrobiologybioRxivMay 21, 2020

A natural single-guide RNA repurposes Cas9 to autoregulate CRISPR-Cas expression

R. E. Workman, T. Pammi, B. T. K. Nguyen…·J. W. Modell

The paper shows that a long-form tracrRNA acts as a natural single guide to repress Cas9 expression, revealing a regulatory mechanism in CRISPR-Cas systems.

DOI 10.1016/j.cell.2020.12.017

CRISPR screenexperimental assay