Author

M. J. Stoltzfus

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1 Assay:CRISPR screen· 1

Frequent Co-Authors

J. W. Modell· 2 shared R. E. Workman· 2 shared B. T. K. Nguyen· 1 shared C. W. Euler· 1 shared E. Smith· 1 shared J. Bondy-Denomy· 1 shared L. W. Graeff· 1 shared N. C. Keith· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMicrobiology

J. W. Modell

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2 papers

Recent·Most cited

MicrobiologybioRxivOct 22, 2023

Anti-CRISPR proteins trigger a burst of CRISPR-Cas9 expression that enhances phage defense

R. E. Workman, M. J. Stoltzfus, N. C. Keith…·J. W. Modell

The paper shows anti-CRISPR proteins in S. pyogenes reduce Cas9 autorepression, leading to increased CRISPR-Cas expression and enhanced phage defense.

DOI 10.1016/j.celrep.2024.113849

bacteria (other)experimental assay

𝕏 PostBluesky

MicrobiologybioRxivMay 21, 2020

A natural single-guide RNA repurposes Cas9 to autoregulate CRISPR-Cas expression

R. E. Workman, T. Pammi, B. T. K. Nguyen…·J. W. Modell

The paper shows that a long-form tracrRNA acts as a natural single guide to repress Cas9 expression, revealing a regulatory mechanism in CRISPR-Cas systems.

DOI 10.1016/j.cell.2020.12.017

CRISPR screenexperimental assay

𝕏 PostBluesky