Reverse genetic screen identifies malaria parasite genes required for gametocyte-to-sporozoite development in its mosquito host
C. V. Ukegbu, A. R. Gomes, M. Giorgalli, M. Campos, A. J. Bailey, T. R. Besson, O. Billker, D. Vlachou, G. K. Christophides
This study uses a reverse genetic screen in Plasmodium berghei to identify genes essential for gametocyte-to-sporozoite development in the mosquito Anopheles coluzzii, confirming prior findings and discovering new genes involved in key stages of the parasite lifecycle.
bioRxiv · Mar 14, 2023 · PreprintMicrobiology