Cell-based production of Fc-GlcNAc and Fc-alpha-2,6 sialyl glycan enriched antibody with improved effector functions through glycosylation pathway engineering
H.-W. Huang, C.-H. Wong, V. S. Shivatare, T.-H. Tseng
This study develops two methods to produce antibodies with homogeneous Fc-SCT glycans, improving effector functions through glycosylation pathway engineering in cell lines.
bioRxiv · Dec 18, 2023 · PreprintBiochemistry