Lineage-specific transcription factor CEBPA accelerates RNA Polymerase I dynamics
Charles Antony A, Santosh Adhikari, Subin S. George, Taejun Son, Kaeli M. Mathias, Frédéric Lessard, Tom Moss, Mustafa Mir, Vikram R. Paralkar
This study shows that the myeloid transcription factor CEBPA accelerates RNA Polymerase I dynamics at rDNA repeats by modulating promoter escape, Pol I accumulation, and DNA supercoiling resolution.
bioRxiv · Oct 27, 2026 · PreprintMolecular Biology