Author

Tao Wu

Beijing Hua Xin Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Bioinformatics· 1 Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Die Qiu· 1 shared Guojun HouiD· 1 shared Haiyan Huang· 1 shared Haopeng WangiD· 1 shared Huaijin Feng· 1 shared Jin ZhuiD· 1 shared Jing Chen· 1 shared Kaixuan DiaoiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperBioinformatics

Die Qiu

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3 papers

Recent·Most cited

Epigenetic regulation of alveolar macrophage homeostasis by histone deacetylase 1 and 2

Wenlong Lai, Maocai Luo, Yuchen Wang, Yuanhao Wang, Xiaoli Li, Zhimin He, Qi Cui, Tao Wu, Li Wu

This study shows HDAC1 and HDAC2 are essential for alveolar macrophage homeostasis by suppressing Bim expression and co-regulating differentiation with LSD1.

Immunity & Inflammation · Oct 18, 2026Peer-reviewedImmunology

TcrDesign: De novo design of epitope specific full-length T cell receptors

Kaixuan Diao, Jing Chen, Xiangyu Zhao, Tao Wu, Die Qiu, W Wang, Haopeng Wang, Xue-Song Liu

TcrDesign generates experimentally validated, functional, full-length TCRs using deep learning, achieving state-of-the-art performance in binding prediction and sequence generation.

Science China Life Sciences · Apr 28, 2026Peer-reviewedBioinformatics

DNA sequence quantitatively encodes CTCF-binding affinity at genome scale

Zihang Yin, Yefan Wang, Guojun Hou, Yuqiao Chen, Huaijin Feng, Jin Zhu, Yufan Xie, Ruoxi Wang, Zhiyu Zhang, Tao Wu, Haiyan Huang, Sheila Q. Xie, Wuming Wang, Wenchao Gu, Qiang Wu, , Ya Guo

The paper experimentally measures CTCF-binding affinity across 276,765 human DNA sequences and develops a deep learning model to predict and interpret binding strength based on sequence features.

bioRxiv · Jan 5, 2026 · PreprintGenomics