Author

Wenlong Lai

Tsinghua University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Chenyun QianiD· 1 shared Haoran AniD· 1 shared Jiao HuiD· 1 shared Jing‐Ren ZhangiD· 1 shared Li Juan WuiD· 1 shared Li Wu· 1 shared Maocai Luo· 1 shared Qi Cui· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

Chenyun QianORCID

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2 papers

Recent·Most cited

Epigenetic regulation of alveolar macrophage homeostasis by histone deacetylase 1 and 2

Wenlong Lai, Maocai Luo, Yuchen Wang, Yuanhao Wang, Xiaoli Li, Zhimin He, Qi Cui, Tao Wu, Li Wu

This study shows HDAC1 and HDAC2 are essential for alveolar macrophage homeostasis by suppressing Bim expression and co-regulating differentiation with LSD1.

Immunity & Inflammation · Oct 18, 2026Peer-reviewedImmunology

Influenza Virus Enhances Bacterial Growth in the Lungs through Weakening Capsule Receptor-Mediated Bacterial Capture by Neutrophils

Yujie Fang, Wenxia Ma, Chenyun Qian, Jiao Hu, Xianbin Tian, Xueting Huang, Wenlong Lai, Li Juan Wu, Haoran An, Jing‐Ren Zhang

This study shows influenza virus weakens neutrophil capture of low-virulence Streptococcus pneumoniae by reducing capsule receptor-mediated complement activation, enhancing bacterial survival and virulence.

bioRxiv · Nov 8, 2024 · PreprintMicrobiology