Epstein-Barr virus nuclear antigen 2 (EBNA2) extensively rewires the human chromatin landscape at autoimmune risk loci
Ted Hong, Sreeja Parameswaran, Omer A. Donmez, Daniel Miller, Carmy R. Forney, Michael Lape, Mariana Saint Just Ribeiro, Jun Liang, Lee Edsall, Albert Frank Magnusen, William E. Miller, Iouri Chepelev, John B. Harley, Bo Zhao, Leah Claire Kottyan, Matthew T. Weirauch
This study shows EBNA2 alters chromatin structure and gene expression at autoimmune risk loci, linking viral infection to genetic risk mechanisms in autoimmune diseases.
Genome Research · Dec 1, 2021Peer-reviewedGenomics