Transmission-blocking activity of artesunate, chloroquine and methylene blue on Plasmodium vivax gametocytes.
Victor Chaumeau, Praphan Wasisakun, James A Watson, Thidar Oo, Sarang Aryalamloed, Mu Phang Sue, Gay Nay Htoo, Naw Moo Tha, Laypaw Archusuksan, Sunisa Sawasdichai, Gornpan Gornsawun, Somya Mehra, Nicholas John White, François Henry Nosten
This study evaluates the transmission-blocking effects of artesunate, chloroquine, and methylene blue on Plasmodium vivax gametocytes, finding that only artesunate and methylene blue significantly reduce oocyst and sporozoite development.
Antimicrobial Agents and Chemotherapy · Jul 26, 2024Peer-reviewedMicrobiology