Dietary fructose promotes anxiety through impairment of microglia physiology
Adeline Coursan, Thomas Devos, Mathilde Huart, Sandrine Ellero‐Simatos, Maguelonne Peffault de Latour, Shingo Nakajima, Stephanie E. Fulton, Sophie Layé, Thierry Alquier, Charlotte Madore-Delpech, Véronique Douard, Xavier Fioramonti
This study shows that dietary fructose causes anxiety by impairing microglia function, with sex-specific effects on metabolism and behavior.
bioRxiv · Oct 27, 2026 · PreprintNeuroscience