Author

Thomas McLellan

Pfizer (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:protein structure· 1

Frequent Co-Authors

Alexandre Esadze· 1 shared Alexey V. GribenkoiD· 1 shared Annaliesa S. AndersoniD· 1 shared Arthur Illenberger· 1 shared Christopher Ponce· 1 shared David R. Keeney· 1 shared Huixian WuiD· 1 shared J. Jasti· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

Alexandre Esadze

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Structure-Based Design of a Highly Immunogenic, Conformationally Stabilized FimH Antigen for a Urinary Tract Infection Vaccine

Natalie C. Silmon de Monerri, Ye Che, Joshua A. Lees, J. Jasti, Huixian Wu, Matthew C. Griffor, Srinivas Kodali, Julio Cesar Hawkins, Jacqueline Lypowy, Christopher Ponce, Kieran Curley, Alexandre Esadze, Juan Guillermo Cárcamo, Thomas McLellan, David R. Keeney, , Robert G. K. Donald

The paper designs a conformationally stabilized FimH antigen for a UTI vaccine, showing improved immunogenicity and structural similarity to native FimH.

PLoS Pathogens · Feb 19, 2025Peer-reviewedMicrobiology