Plasma untargeted metabolomics reveals distinct metabolic disturbances between sexes following inhalation of ultrafine particles and exposure to aircraft noise in mice
Thuy Thi Lai, Aino‐Kaisa Piironen, Elena Puris, Veronika Górová, Mika Ihalainen, Tuukka Kokkola, Jiayin Zheng, Thomas Muenzel, Andreas Daiber, Pasi Jalava, Olli Sippula, Katja Kanninen
This study uses metabolomics to show that UFP and aircraft noise exposure cause sex-specific metabolic changes in mice, with AN having the greatest impact and combined exposure showing sex-dependent effects.
bioRxiv · Nov 1, 2026 · PreprintPharmacology & Toxicology