Extrinsic Apoptosis and Necroptosis in Telencephalic Development: A Single-Cell Mass Cytometry Study
Jiachen Shi, Weile Liu, Alison Song, Timi Sanni, Amy Lynnette Van Deusen, Eli R. Zunder, Christopher D. Deppmann
This study uses single-cell mass cytometry to show that deleting RIPK3 and Caspase-8 increases cell count in the mouse telencephalon, indicating non-exclusive roles for extrinsic apoptosis and necroptosis in developmental cell elimination.
Cell Death and Differentiation · Oct 21, 2025Peer-reviewedDevelopmental Biology