Author

Todd Holyoak

University of Waterloo;Primary ORCID profile (0000-0002-7329-1115 · 2 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Todd HolyoakiD2 papers · University of Waterloo

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

Alexander M Ille· 1 shared Anetta L Ille· 1 shared Hannah H Lamont· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperBioinformatics

Alexander M Ille

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1 paper

Recent·Most cited

AI-based structural modelling and pathogenic variant mapping across the human protein interactome

Alexander M Ille, Anetta L Ille, Hannah H Lamont, Todd Holyoak

The paper uses AI to model 109,282 human protein interactions, maps pathogenic variants to these structures, and identifies interface mutations in disease contexts.

bioRxiv · Nov 3, 2026 · PreprintBioinformatics