BioinformaticsbioRxivPreprint
AI-based structural modelling and pathogenic variant mapping across the human protein interactome
Alexander M Ille, Anetta L Ille, Hannah H Lamont, Todd Holyoak
The paper uses AI to model 109,282 human protein interactions, maps pathogenic variants to these structures, and identifies interface mutations in disease contexts.
DOI 10.64898/2026.10.28.762585