Author

U. Mechold

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Assay:structural biology· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. A. Missinou· 1 shared A. Belyy· 1 shared C. Velours· 1 shared D. Ladant· 1 shared D. Raoux-Barbot· 1 shared F. Merino· 1 shared L. Renault· 1 shared M. Comisso· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBiochemistry

A. A. Missinou

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Author profile →

2 papers

Recent·Most cited

Functional and structural insights into the multi-step activation and catalytic mechanism of bacterial ExoY nucleotidyl cyclase toxins bound to actin-profilin

M. Teixeira-Nunes, P. Retailleau, D. Raoux-Barbot, M. Comisso, A. A. Missinou, C. Velours, S. Plancqueel, D. Ladant, U. Mechold, L. Renault

This paper investigates the activation and catalytic mechanism of ExoY toxins by analyzing their interaction with actin and profilin, revealing structural insights into their multi-step activation process.

bioRxiv · Jan 13, 2023 · PreprintBiochemistry

Mechanism of actin-dependent activation of nucleotidyl cyclase toxins from bacterial human pathogens

A. Belyy, F. Merino, U. Mechold, S. Raunser

The paper investigates how actin interacts with nucleotidyl cyclase toxins from bacterial pathogens to activate them, revealing structural changes and allosteric mechanisms.

bioRxiv · Jun 27, 2021Biochemistry