Multimodal single-cell profiling reveals cancer crosstalk between macrophages and stromal cells in poor prognostic cholangiocarcinoma patients.
L. R. Heij, Sikander Hayat, Konrad Reichel, Sidrah Maryam, Colm J. O’Rourke, Xiuxiang Tan, Marlous van den Braber, Jan Verhoeff, Maurice Halder, Fabian Peisker, Georg Wiltberger, Jan Bednarsch, Daniel Heise, Julia Campello Deierl, Sven A. Lang, , Ulf Neumann
This study uses multimodal single-cell profiling to identify immune cell crosstalk mechanisms in poor prognostic cholangiocarcinoma, revealing key ligand pairs and pathways contributing to immune exhaustion.
bioRxiv · Feb 3, 2024Cancer Biology