Remodeling of Il4-Il13-Il5 locus underlies selective gene expression
H. Nagashima, F. Petermann, A. Pekowska, V. Chaitankar, Y. Kanno, J. J. O'Shea
The paper shows that the Il4-Il13-Il5 locus remodels its 3D structure in ILC2 and Th2 cells, leading to distinct cytokine expression patterns.
bioRxiv · Jul 22, 2022Immunology