Optimized liquid and gas phase fractionation increase HLA-peptidome coverage for primary cell and tissue samples
S. Klaeger, A. Apffel, K. R. Clauser, S. Sarkizova, G. Oliveira, S. Rachimi, P. M. Le, A. Tarren, V. Chea, J. G. Abelin, D. A. Braun, P. A. Ott, H. Keshishian, N. Hacohen, D. Keskin, , S. A. Carr
The paper improves HLA-peptidome coverage using optimized liquid and gas phase fractionation methods, enabling detection of more peptides from limited clinical tissue samples.
bioRxiv · May 25, 2021Biochemistry