A microfluidics-assisted methodology for label-free isolation of CTCs with downstream methylation analysis of cfDNA in lung cancer
A. Carvalho, C. Guimaraes-Teixeira, V. Constancio, M. Fernandes, C. Macedo-Silva, R. Henrique, F. J. Monteiro, C. Jeronimo
This study develops a microfluidic method for label-free CTC isolation and cfDNA methylation analysis in lung cancer patients, showing improved diagnostic and prognostic potential through biomarker combinations.
bioRxiv · Feb 28, 2022 · PreprintBioengineering