Author

V. John

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. J. O'Donoghue· 1 shared A. N. Floyd· 1 shared B. Barrios· 1 shared B. Jagodzinska· 1 shared C. Yeun· 1 shared C.-S. Hsieh· 1 shared D. H. Kulkarni· 1 shared D. L. Harris· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMicrobiology

A. J. O'Donoghue

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2 papers

Recent·Most cited

Small Intestinal Goblet Cells Control Humoral Immune Responses and Mobilization During Enteric Infection.

D. H. Kulkarni, K. B. Talati, E. L. Joyce, H. Kousik, D. L. Harris, A. N. Floyd, V. Vavrinyuk, B. Barrios, S. Udayan, K. G. McDonald, V. John, C.-S. Hsieh, R. D. Newberry

This study shows that inhibiting goblet cell-associated antigen passages (GAPs) during enteric infection promotes mucosal humoral immunity by mobilizing plasma cells, but requires a second signal for full IgA secretion.

bioRxiv · Jan 6, 2024 · PreprintImmunology

Identification of a Papain-Like Protease Inhibitor with Potential for Repurposing in Combination with an Mpro Protease Inhibitor for Treatment of SARS-CoV-2

J. Campagna, B. Jagodzinska, P. Alvarez, C. Yeun, P. Spilman, K. M. Enquist, W. Cohn, P. Fajtov, A. J. O'Donoghue, V. Arumugaswami, M. M. H. Li, R. Damoiseaux, V. John

The paper identifies eltrombopag as a PLpro inhibitor that can be repurposed for SARS-CoV-2 treatment, effective in combination with Mpro inhibitors.

bioRxiv · Jul 18, 2022Microbiology