Author

V. Kremling

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:structural biology· 2 Research Focus:drug response / drug discovery· 1 Research Focus:protein structure prediction· 1 Organism:virus· 1

Frequent Co-Authors

B. Klopprogge· 2 shared H. N. Chapman· 2 shared A. Henkel· 1 shared A. Kiene· 1 shared A. Munke· 1 shared A. P. Mancuso· 1 shared A. Rahmani· 1 shared B. Federici· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiochemistry

B. Klopprogge

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Author profile →

2 papers

Recent·Most cited

SARS-CoV-2 methyltransferase nsp10-16 in complex with natural and drug-like purine analogs for guiding structure-based drug discovery

V. Kremling, S. Falke, Y. Fernandez-Garcia, C. Ehrt, A. Kiene, B. Klopprogge, T. E. S. Scheer, F. Barthels, P. Middendorf, S. Kuehn, S. Guenther, M. Rarey, H. N. Chapman, D. Oberthuer, J. Sprenger

The paper identifies ligands binding to the SARS-CoV-2 nsp10-16 complex using X-ray crystallography and reports their structures, providing insights for drug discovery.

bioRxiv · Mar 13, 2024 · PreprintBiochemistry

Structure of the Lysinibacillus sphaericus Tpp49Aa1 pesticidal protein elucidated from natural crystals using MHz-SFX

L. J. Williamson, M. Galchenkova, H. L. Best, R. J. Bean, A. Munke, S. Awel, G. Pena, J. Knoska, R. Schubert, K. Doerner, H.-W. Park, D. K. Bideshi, A. Henkel, V. Kremling, B. Klopprogge, , D. Oberthur

This paper determines the structure of Tpp49Aa1 using MHz-SFX and investigates its interaction with Cry48Aa1, expanding its known target range to include additional mosquito species.

bioRxiv · Jan 14, 2022 · PreprintBiochemistry