Author

V. Lok

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

A. Ribas· 1 shared C. G. Radu· 1 shared E. R. Abt· 1 shared G. Abril-Rodriguez· 1 shared J. Czernin· 1 shared J. R. Capri· 1 shared S. Poddar· 1 shared T. M. Le· 1 shared

Activity by Year

2019-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. Ribas

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1 paper

Recent·Most cited

Defective Nucleotide Catabolism Defines a Subset of Cancers Sensitive to Purine Nucleoside Phosphorylase Inhibition

E. R. Abt, V. Lok, T. M. Le, S. Poddar, W. Kim, J. R. Capri, G. Abril-Rodriguez, T. R. Donahue, J. Czernin, T. Mehrling, A. Ribas, C. G. Radu

This study identifies SAMHD1, dCK, and CDA as biomarkers for predicting sensitivity to PNP inhibitors in cancers, showing that PNP inhibition can target both hematological and solid tumors.

bioRxiv · Nov 4, 2019 · PreprintCancer Biology