Patient phenotypes and their relation to TNFα signaling and immune cell composition in critical illness and autoimmune disease
V. Krishna, H. Banie, N. Conceicao-Neto, Y. Murata, I. Verbrugge, V. Trifonov, R. Martinez, V. Murali, Y.-c. Lee, R. D. May, I. Najera, A. Fowler, C. K. F. Li
The paper identifies a hyper-inflammatory phenotype linked to TNF signaling and mature neutrophils in critical illness and autoimmune disease using machine learning and patient data.
bioRxiv · Oct 30, 2023 · PreprintImmunology