Author

Y.-C. Lee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cancer Biology· 2 Immunology· 1 Microbiology· 1 Pathology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:proteomics· 4 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

C. J. Logothetis· 2 shared G. Yu· 2 shared J. H. Song· 2 shared L.-y. Yu-Lee· 2 shared S.-C. Lin· 2 shared S.-H. Lin· 2 shared T. Panaretakis· 2 shared A. Fowler· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersCancer Biology

C. J. Logothetis

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Patient phenotypes and their relation to TNFα signaling and immune cell composition in critical illness and autoimmune disease

V. Krishna, H. Banie, N. Conceicao-Neto, Y. Murata, I. Verbrugge, V. Trifonov, R. Martinez, V. Murali, Y.-c. Lee, R. D. May, I. Najera, A. Fowler, C. K. F. Li

The paper identifies a hyper-inflammatory phenotype linked to TNF signaling and mature neutrophils in critical illness and autoimmune disease using machine learning and patient data.

bioRxiv · Oct 30, 2023 · PreprintImmunology

The Non-Phototrophic Hypocotyl3 (NPH3)-domain protein NRL5 is a trafficking-associated GTPase essential for drought resistance.

N. UPADHYAY-TIWARI, X.-J. Huang, Y.-C. Lee, S. K. Singh, C.-C. Hsu, S.-S. Huang, P. E. Verslues

The paper identifies NRL5, an NPH3-domain protein with GTPase activity, as essential for drought resistance by regulating proline catabolism and trafficking interactions.

bioRxiv · May 10, 2023 · PreprintPlant Biology

Activation of retinoic acid receptor reduces metastatic prostate cancer bone lesions through blocking endothelial-to-osteoblast transition

G. Yu, P. G. Corn, P. Shen, J. H. Song, Y.-C. Lee, S.-C. Lin, J. Pan, S. K. Agarwal, T. Panaretakis, M. Pacifici, C. J. Logothetis, L.-y. Yu-Lee, S.-H. Lin

bioRxiv · Dec 22, 2021Cancer Biology

Prostate tumor-induced stromal reprogramming generates Tenascin C that promotes prostate cancer metastasis through YAP/TAZ inhibition

S.-H. Lin, Y.-C. Lee, S.-C. Lin, G. Yu, M. Zhu, J. H. Song, K. Rivera, D. J. Pappin, C. J. Logothetis, T. Panaretakis, G. Wang, L.-y. Yu-Lee

This study shows that prostate tumor-induced stromal reprogramming produces Tenascin C, which promotes metastasis by inhibiting YAP/TAZ through 5{beta}1 integrin.

bioRxiv · Nov 8, 2021Cancer Biology

Glycan-masking spike antigen in NTD and RBD elicits broadly neutralizing antibodies against SARS-CoV-2 variants

W.-S. Lin, I.-C. Chen, H.-C. Chen, Y.-C. Lee, S.-C. Wu

This study shows that glycan-masking of SARS-CoV-2 NTD and RBD antigens increases neutralizing antibody titers against multiple variants.

bioRxiv · Nov 1, 2021Microbiology

De Novo Discovery of High Affinity Peptide Binders for the SARS-CoV-2 Spike Protein

S. Pomplun, M. Jbara, A. J. Quartararo, G. Zhang, J. S. Brown, Y.-C. Lee, X. Ye, S. Hanna, B. L. Pentelute

This paper identifies high-affinity peptide binders for the SARS-CoV-2 spike protein using affinity selection-mass spectrometry, with nanomolar affinities and selectivity over human serum proteins.

bioRxiv · Sep 29, 2020Bioengineering

Segmentation boosting with compensation methods in optical coherence tomography angiography images

Y.-C. Lee, J.-J. Ding, L. Yeung, T.-W. Lee, C.-J. Chang, Y.-T. Lin, R. Y. Chang

This study introduces a novel method to improve blood vessel detection in OCT angiography images by compensating for motion artifacts using a modified U-Net architecture.

bioRxiv · Aug 20, 2020 · PreprintBioengineering

Impact of urolithiasis and hydronephrosis on acute kidney injury in patients with urinary tract infection

C.-Y. Hsiao, T.-H. Chen, Y.-C. Lee, M.-C. Wang

This study examines the impact of urolithiasis and hydronephrosis on acute kidney injury in patients with urinary tract infection, finding that ureteral stones with hydronephrosis significantly increase AKI risk.

bioRxiv · Jul 13, 2020 · PreprintPathology