FANCD2 tunes the UPR preventing mitochondrial stress-induced common fragile site instability.
P. Fernandes, B. Miotto, C. Saint-Ruf, V. Nahse, S. Ravera, E. Cappelli, V. Naim
This study shows FANCD2 stabilizes common fragile sites by modulating the UPR, preventing mitochondrial stress-induced genomic instability.
bioRxiv · Oct 18, 2019 · PreprintCell Biology