P. Fernandes

Vagus nerve mediated liver-brain axis is a major regulator of the metabolic landscape in the liver

This study investigates the role of the vagus nerve in regulating liver metabolism, finding that its ablation alters hepatic proteome and promotes lipid accumulation and steatosis.

Validation of the in-house designed one-trial inhibitory avoidance test for two strains of adult zebrafish

The paper validates an open-source one-trial inhibitory avoidance test for two zebrafish strains, showing it effectively measures memory with a robust and long-lasting response.

Assessing changes in global fire regimes

This study assesses changes in global fire regimes using expert opinions, finding increased fire regime change rates and future intensification under higher emission scenarios.

Experimentally induced drought and growing season stage modulate community-level functional traits in a temperate grassland

The paper examines how drought and growing season timing affect functional traits in a temperate grassland, finding significant trait changes in drought conditions post-cutting.

Drivers and implications of the extreme 2022 wildfire season in Southwest Europe

The paper analyzes the extreme 2022 wildfire season in southwest Europe, finding record-breaking fuel dryness and early fire onset linked to climate change.

Flexible estimation of biodiversity with short-range multispectral imaging in a temperate grassland

This study uses multispectral imaging from drones to estimate biodiversity metrics in a grassland, finding that spectral radiance variation correlates with biodiversity indices.

The AMA1-RON complex drives Plasmodium sporozoite invasion in the mosquito and mammalian hosts

This study shows that the AMA1-RON complex is essential for Plasmodium sporozoite invasion of mosquito salivary glands and mammalian hepatocytes, supporting its role in parasite transmission.

Plasmodium sporozoites require the protein B9 to invade hepatocytes

This study identifies B9 as a critical protein for Plasmodium sporozoite invasion of hepatocytes, revealing structural and functional similarities to merozoite invasion complexes.

Developmental changes and metabolic reprogramming during establishment of infection and progression of Trypanosoma brucei brucei through its insect host

This paper presents a genome assembly and transcriptome analysis of T. brucei brucei EATRO1125, revealing developmental changes and metabolic reprogramming during its life cycle in the tsetse fly.

A measles-vectored COVID-19 vaccine induces long-term immunity and protection from SARS-CoV-2 challenge in mice

The dimerisable Cre recombinase allows conditional genome editing in the mosquito stages of Plasmodium berghei

This paper implements a dimerisable Cre recombinase system in Plasmodium berghei to enable conditional genome editing in both mammalian and mosquito stages of the parasite.

FANCD2 tunes the UPR preventing mitochondrial stress-induced common fragile site instability.

This study shows FANCD2 stabilizes common fragile sites by modulating the UPR, preventing mitochondrial stress-induced genomic instability.