Monocyte Adhesion and Transmigration Through Endothelium Following Cardiopulmonary Bypass Shearing is Mediated by IL-8 Signaling
H. Zhou, L. N. Tu, C. M. Giachelli, V. Nigam, M. Scatena
bioRxiv · Jun 5, 2023 · PreprintCell Biology
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H. Zhou, L. N. Tu, C. M. Giachelli, V. Nigam, M. Scatena
bioRxiv · Jun 5, 2023 · PreprintCell Biology
W. Li, L. N. Tu, L. Hsieh, J. R. Smith, Y.-T. Yeh, A. Sinyagin, M. Ghassemian, A. Timms, K. Charette, D. Mauchley, M. McMullan, L. Bohuta, C. Greene, M. Regier, J. C. del Alamo, , V. Nigam
The paper identifies SPTAN1 and RAF1 as genes activated by shear stress during cardiopulmonary bypass, leading to inflammation and cell death through store-operated calcium entry.
bioRxiv · May 4, 2022 · PreprintCell Biology