Single Cell Transcriptomics-guided Antisense Treatment Improves Endoderm Differentiation of iPSCs
P. Hor, V. Punj, Z. Borok, A. Ryan, J. Ichida
The paper develops a method to enhance endoderm differentiation of iPSCs by suppressing transcription factors identified through single-cell RNA sequencing, increasing endodermal cell yield by up to 20-fold.
bioRxiv · May 13, 2020 · PreprintCell Biology