Evolutionary repurposing of trypanosomal Pam18 and Pam16 reveals a new regulatory circuit for mitochondrial genome replication
C. von Känel, S. Oeljeklaus, S. Calderaro, I. M. Durante, V. Raskova, B. Warscheid, A. Schneider
This study shows that TbPam16 and TbPam18 in Trypanosoma brucei regulate maxicircle replication in mitochondria through a novel regulatory circuit involving MaRF11 and proteasomal control.
bioRxiv · Dec 5, 2023 · PreprintBiochemistry