Direction of actin flow dictates integrin LFA-1 orientation during leukocyte migration
P. Nordenfelt, T. I. Moore, S. B. Mehta, J. M. Kalappurakkal, V. Swaminathan, N. Koga, T. J. Lambert, D. Baker, J. C. Waters, R. Oldenbourg, T. Tani, S. Mayor, C. M. Waterman, T. A. Springer
The paper shows that integrin orientation is dictated by actin flow direction and cytoskeletal forces during leukocyte migration.
bioRxiv · Aug 27, 2016Cell Biology