Unravelling the roadblocks to 1,2-propanediol biosynthesis in select solventogenic Clostridium species
E. Agyeman-Duah, S. Kumar, V. Ujor
This study investigates the challenges in producing 1,2-propanediol using solventogenic Clostridium species, finding that recombinant strains fail to convert intermediates efficiently and that regulatory mechanisms may limit methylglyoxal pathway activity.
bioRxiv · Feb 22, 2024 · PreprintMicrobiology