Liquid plug propagation in computer-controlled microfluidic airway-on-a-chip with semi-circular microchannels
H. Viola, V. Vasani, K. Washington, J. H. Lee, C. Selva, A. Li, C. J. Llorente, Y. Murayama, J. B. Grotberg, F. Romano, S. Takayama
This paper presents a lung-on-a-chip device that enables systematic study of liquid plug dynamics in distal airways, showing effects of surfactant, viscosity, and channel geometry on plug propagation and epithelial cell injury.
bioRxiv · May 24, 2023Bioengineering