Author

Vania Morales

Buck Institute for Research on Aging

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Claudio A. HetziD· 2 shared Birgit SchillingiD· 1 shared Cameron Wehrfritz· 1 shared Claudia SepúlvedaiD· 1 shared Claudia Sepúlveda-Quiñenao· 1 shared Daniela Becerra· 1 shared Giovanni Tamburini· 1 shared Grant Kauwe· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersMolecular Biology

Claudio A. HetzORCID

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2 papers

Recent·Most cited

Oral administration of dibenzoylmethane (DBM) prevents cognitive decline in a C9ORF72-mediated FTD mouse model

Paulina Torres, Daniela Becerra, José I. Astorga, Matías Fuentealba, Grant Kauwe, Luis Gonzalez, Guillermo Diaz, Vania Morales, Vicente Valenzuela, Cameron Wehrfritz, Yani Y. Ngwala, Claudia Sepúlveda-Quiñenao, Samah Shah, Joanna Bons, Leonard Petrucelli, , Claudio A. Hetz

This study shows that oral DBM treatment prevents cognitive decline in a C9ORF72 FTD mouse model without altering protein inclusions but corrects gene expression changes related to cytoskeleton, ALS, and metabolism.

bioRxiv · Aug 10, 2026 · PreprintMolecular Biology

BAX and BAK expression triggers multiple IRE1 signaling outputs under ER stress

Claudia Sepúlveda, Mateus Milani, Vania Morales, Giovanni Tamburini, Nicolas Montes, Claudio A. Hetz

This study shows that BAX and BAK deficiency increases ER stress threshold for XBP1 splicing and reduces RIDD substrate degradation and IRE1 phosphorylation.

bioRxiv · Mar 26, 2024 · PreprintCell Biology