Comparison of Three Transcytotic Pathways for Distribution to Brain Metastases of Breast Cancer.
I. Khan, B. Gril, A. Paranjape, C. Robinson, S. Difilippantonio, W. Biernat, M. Bienkowski, R. Peksa, R. Duchnowska, J. Jassem, P. K. Brastianos, P. Metellus, E. Bialecki, C. C. Woodroofe, H. Wu, , P. S. Steeg
This study compares three transcytotic pathways for drug delivery to brain metastases of breast cancer and finds that albumin shows optimal distribution and uses a novel clathrin-independent endocytosis mechanism.
bioRxiv · Aug 9, 2022Cancer Biology