Force-induced changes of PilY1 drive surface sensing by Pseudomonas aeruginosa
S. Webster, M. Mathelie-Guinlet, A. Verissimo, D. Schultz, A. Viljoen, C. K. Lee, W. C. Schmidt, G. Wong, Y. Dufrene, G. OToole
This study shows that force-induced conformational changes in PilY1, a TFP tip protein, are required for surface sensing in Pseudomonas aeruginosa, affecting c-di-GMP signaling and biofilm formation.
bioRxiv · Aug 24, 2021Microbiology