ImmunologybioRxiv
Metabolic and functional impairment of CD8+ T cells from the lungs of influenza-infected obese mice
W. D. Green, A. E. Al-Shaer, Q. Shi…·S. R. Shaikh
This study shows that diet-induced obesity impairs pulmonary CD8+ T cell metabolism and function during influenza infection, leading to reduced effector cells and cytokine production.
DOI 10.1002/jlb.4a0120-075rr