Utilisation of staphylococcal immune evasion protein Sbi as a novel vaccine adjuvant
Y. Yang, C. Back, M. Graewert, A. Wahid, H. Denton, R. Kildani, J. Paulin, K. Woerner, W. Kaiser, D. I. Svergun, A. Sartbaeva, A. Watts, K. Marchbank, J. M. van den Elsen
This paper demonstrates that the Staphylococcal protein Sbi can be used as a vaccine adjuvant by promoting natural opsonisation of antigens with C3 fragments, enhancing immune responses.
bioRxiv · Sep 10, 2018Biochemistry